Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGAV | P06756 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043860 | 0.90 | ITGB3 (0.52) | ITGB3ITGAVSMN1; SMN2TSHRHDAC3 | |
| SCHEMBL8250421 | 0.89 | ITGB3 (0.51) | ITGB3ITGAVTLR8NPC1RAB9A | |
| SCHEMBL8042662 | 0.83 | ITGB3 (0.73) | ITGB3ITGAVSMN1; SMN2TSHR | |
| SCHEMBL8047151 | 0.80 | ITGB3 (0.59) | ITGB3ITGAVSMN1; SMN2TSHRTLR8 | |
| SCHEMBL8043750 | 0.80 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL3860530 | 0.78 | TLR8 (0.61) | ITGB3ITGAVSMN1; SMN2TLR8NPC1 | |
| SCHEMBL8044809 | 0.76 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL8032379 | 0.75 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL8033060 | 0.74 | ITGB3 (0.75) | ITGB3ITGAVSMN1; SMN2TSHRNPC1 | |
| SCHEMBL11947882 | 0.74 | PARP1 (0.48) | ITGB3ITGAVTSHRTLR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001249-A1 | NITROGEN HETEROCYCLE BIARYLS FOR OSTEOPOROSIS AND OTHER DISEASES | PHARMACOPEIA, INC. (US) | 2007-01-04 | — | — | WO | disclosed |