Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 12/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132664 | 1.00 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL763030 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL13635811 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL15106702 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL754149 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL12159997 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL17563566 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL15127692 | 0.91 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL12104873 | 0.87 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL16948498 | 0.87 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143301-B2 | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100260708-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100260708-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | MAPK13 3291/4885MAPK12 3437/4885MAPK11 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.