Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13148519 | 0.86 | DPP4 (0.48) | DPP4DPP8DPP9PKMFAP | |
| SCHEMBL4138799 | 0.81 | NPC1 (0.50) | DPP4CYP3A4NPC1ALDH1A1 | |
| SCHEMBL3878156 | 0.79 | PKM (0.47) | DPP4DPP8DPP9PKMFAP | |
| SCHEMBL678338 | 0.79 | GRIN2D (0.59) | DPP4DPP8DPP9PKMFAP | |
| SCHEMBL9918349 | 0.79 | GRIN2D (0.59) | DPP4DPP8DPP9PKMFAP | |
| SCHEMBL9918883 | 0.79 | GRIN2D (0.59) | DPP4DPP8DPP9PKMFAP | |
| SCHEMBL19909617 | 0.78 | DPP4 (0.70) | DPP4DPP8DPP9FAPPITRM1 | |
| SCHEMBL2761236 | 0.77 | PKM (0.45) | DPP4DPP8DPP9PKMFAP | |
| 3-Hydroxyrimantadine SCHEMBL2739148 | 0.76 | SLC22A2 (0.59) | DPP4DPP8DPP9PKMFAP | |
| 3-Hydroxyrimantadine SCHEMBL12855162 | 0.76 | SLC22A2 (0.59) | DPP4DPP8DPP9PKMFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222242-A1 | Process for preparing a dipeptidyl peptidase IV inhibitor and intermediates employed therein | ASTRAZENECA AB (SE) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222242-A1 | Process for preparing a dipeptidyl peptidase IV inhibitor and intermediates employed therein | DPP4, DPP8, DPP7 | DPP4 1/4885DPP8 2/4885DPP9 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.