Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | BACE1 | P56817 | 5/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | KIF5B | P33176 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520659 | 0.94 | PDE10A (0.42) | PDE10AACHEBACE1PDGFRBPDGFRA | |
| SCHEMBL4761261 | 0.87 | ACHE (0.49) | PDE10AACHEBACE1PDGFRBPDGFRA | |
| SCHEMBL14520664 | 0.86 | PDE10A (0.43) | PDE10AACHEBACE1PDGFRBRET | |
| SCHEMBL8250709 | 0.84 | ACHE (0.44) | PDE10AACHEBACE1PDGFRBPDGFRA | |
| SCHEMBL14520661 | 0.83 | ENPP1 (0.45) | PDE10AACHEBACE1PDGFRBPDGFRA | |
| Formic Acid SCHEMBL5470498 | 0.83 | ACHE (0.46) | PDE10AACHEBACE1PDGFRBPDGFRA | |
| SCHEMBL8247455 | 0.82 | PDGFRB (0.44) | PDE10AACHEBACE1PDGFRBPDGFRA | |
| SCHEMBL14520676 | 0.81 | PDE10A (0.42) | PDE10AACHEBACE1PDGFRBRET | |
| SCHEMBL5470503 | 0.81 | ACHE (0.45) | PDE10AACHEBACE1PDGFRBPDGFRA | |
| SCHEMBL8247196 | 0.79 | ACHE (0.48) | PDE10AACHEBACE1RETKIF5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022280-A1 | PHOSPHODIESTERASE 10 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |