SCHEMBL825180

SCHEMBL825180

CCCCCCCCCCCCCCCCCCN(/C=C/N(Cc1ccccn1)Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAPT P10636 1/20 0.47
LIN28A Q9H9Z2 1/20 0.47
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
KDM4E B2RXH2 5/20 0.40
LMNA P02545 2/20 0.40
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
RAB9A P51151 1/20 0.40
TSHR P16473 2/20 0.40
POLB P06746 1/20 0.40
KCNA5 P22460 2/20 0.38
HRH1 P35367 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825404 1.00 SMN1; SMN2 (0.47) SMN1; SMN2TDP1MAPTLIN28ANR1H2
SCHEMBL1332463 1.00 SMN1; SMN2 (0.47) SMN1; SMN2TDP1MAPTLIN28ANR1H2
SCHEMBL825402 1.00 SMN1; SMN2 (0.47) SMN1; SMN2TDP1MAPTLIN28ANR1H2
SCHEMBL825182 1.00 SMN1; SMN2 (0.47) SMN1; SMN2TDP1MAPTLIN28ANR1H2
SCHEMBL1332169 1.00 SMN1; SMN2 (0.47) SMN1; SMN2TDP1MAPTLIN28ANR1H2
SCHEMBL846456 0.94 TDP1 (0.50) SMN1; SMN2TDP1MAPTLIN28ANR1H2
SCHEMBL846458 0.94 TDP1 (0.50) SMN1; SMN2TDP1MAPTLIN28ANR1H2
SCHEMBL5556273 0.82 SMN1; SMN2 (0.61) SMN1; SMN2TDP1MAPTLIN28ALMNA
SCHEMBL5556275 0.82 SMN1; SMN2 (0.61) SMN1; SMN2TDP1MAPTLIN28ALMNA
SCHEMBL135635 0.81 TDP1 (0.68) SMN1; SMN2TDP1MAPTLIN28ANR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US claimed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US claimed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP claimed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US claimed
US-8642685-B2 Liquid hardening OMG UK Technology, Ltd (GB) 2014-02-04 US claimed
US-20130123452-A1 CURING LIQUIDS OMG ADDITIVES LIMITED (UK) 2013-05-16 US claimed
US-20130041079-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2013-02-14 US claimed
EP-2521750-A1 CURING LIQUIDS OMG Additives Limited (GB) 2012-11-14 EP claimed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO claimed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP claimed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP claimed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US claimed
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US disclosed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US disclosed
US-9145501-B2 Coating composition and use thereof PPG EUROPE BV (NL) 2015-09-29 US disclosed
US-9034785-B2 Accelerator solution and process for curing curable resins AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-05-19 US disclosed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP disclosed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP disclosed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US disclosed
EP-2103735-A1 Catalytic bleaching of substrates Unilever PLC (GB) 2009-09-23 EP disclosed