SCHEMBL846458

SCHEMBL846458

CCCCN(C=CN(Cc1ccccn1)Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
LIN28A Q9H9Z2 1/20 0.50
NR1H2 P55055 2/20 0.47
NR1H3 Q13133 2/20 0.47
KDM4E B2RXH2 3/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 1/20 0.40
KCNA5 P22460 2/20 0.40
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
KCNH2 Q12809 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TLR7 Q9NYK1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846456 1.00 TDP1 (0.50) TDP1MAPTSMN1; SMN2LIN28ANR1H2
SCHEMBL825180 0.94 SMN1; SMN2 (0.47) TDP1MAPTSMN1; SMN2LIN28ANR1H2
SCHEMBL1332169 0.94 SMN1; SMN2 (0.47) TDP1MAPTSMN1; SMN2LIN28ANR1H2
SCHEMBL1332463 0.94 SMN1; SMN2 (0.47) TDP1MAPTSMN1; SMN2LIN28ANR1H2
SCHEMBL825404 0.94 SMN1; SMN2 (0.47) TDP1MAPTSMN1; SMN2LIN28ANR1H2
SCHEMBL825182 0.94 SMN1; SMN2 (0.47) TDP1MAPTSMN1; SMN2LIN28ANR1H2
SCHEMBL825402 0.94 SMN1; SMN2 (0.47) TDP1MAPTSMN1; SMN2LIN28ANR1H2
SCHEMBL5556275 0.85 SMN1; SMN2 (0.61) TDP1MAPTSMN1; SMN2LIN28ATSHR
SCHEMBL5556273 0.85 SMN1; SMN2 (0.61) TDP1MAPTSMN1; SMN2LIN28ATSHR
SCHEMBL6864944 0.83 SMN1; SMN2 (0.52) TDP1MAPTSMN1; SMN2LIN28ANR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US claimed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US claimed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP claimed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US claimed
US-8642685-B2 Liquid hardening OMG UK Technology, Ltd (GB) 2014-02-04 US claimed
US-20130123452-A1 CURING LIQUIDS OMG ADDITIVES LIMITED (UK) 2013-05-16 US claimed
US-20130041079-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2013-02-14 US claimed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP claimed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP claimed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US claimed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 US disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 US disclosed
US-11193038-B2 Drier compositions for alkyd resins ALLNEX AUSTRIA GMBH (AT) 2021-12-07 US disclosed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 EP disclosed
EP-2760899-B1 COATING COMPOSITION AND USE THEREOF PPG EUROPE B V (NL) 2020-08-19 EP disclosed
US-8013044-B2 Liquid hardening CONOPCO, INC. (US) 2011-09-06 US disclosed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP disclosed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP disclosed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US disclosed
EP-2103735-A1 Catalytic bleaching of substrates Unilever PLC (GB) 2009-09-23 EP disclosed