1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL8252724

C=C(Cl)Cl.ClCCCl.ClCCl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,1-Dichloroethene SCHEMBL5227583 0.95
1,1-Dichloroethene SCHEMBL6010214 0.91
1,1-Dichloroethene SCHEMBL11347373 0.78 ALDH1A1 (0.47) ALDH1A1TSHRHSD17B10TDP1
1,2-Dichloroethane SCHEMBL8822063 0.74 ALDH1A1 (0.83) ALDH1A1TSHRTDP1
1,2-Dichloroethane SCHEMBL611530 0.74
1,1-Dichloroethene SCHEMBL979464 0.74
1,1-Dichloroethene SCHEMBL7620 0.74
1,1-Dichloroethene SCHEMBL244212 0.74
Tetrachloroethylene SCHEMBL4217450 0.70 TSHR (0.56) ALDH1A1TSHRTDP1
1,1-Dichloroethene SCHEMBL1855244 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165251-A On-line gas chromatograph with sample preparation, concentration, and calibration apparatus for measuring trace organic species from combustor flue gas THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. ENVIRONMENTAL PROTECTION AGENCY (US) 2000-12-26 US disclosed