Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.76 |
| ▸ | DRD1 | P21728 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | PDE4A | P27815 | 1/20 | 0.76 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NECTIN4 | Q96NY8 | 4/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | KCNMB4 | Q86W47 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | SHH | Q15465 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.38 |
| ▸ | NPR1 | P16066 | 1/20 | 0.38 |
| ▸ | NPR3 | P17342 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256936 | 0.97 | CTSL (0.71) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8235984 | 0.95 | CTSL (0.84) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14300849 | 0.94 | CTSL (0.77) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274582 | 0.94 | CTSL (0.78) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8260309 | 0.93 | CTSL (0.73) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8260169 | 0.93 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14177511 | 0.93 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274576 | 0.93 | CTSL (0.78) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274580 | 0.93 | CTSL (0.78) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274907 | 0.93 | CTSL (0.80) | CTSLDRD1PTGS1PDE4AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110185-A2 | ANTIINFECTIVE LIPOPEPTIDES | CUBIST PHARMACEUTICALS, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| WO-2003014147-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |