Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527924 | 0.89 | TDP1 (0.80) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL31016082 | 0.83 | CYP19A1 (0.52) | TDP1ALDH1A1MAPTLMNACYP19A1 | |
| SCHEMBL7167731 | 0.82 | TDP1 (0.69) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL1014744 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL11653963 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL8270572 | 0.80 | TDP1 (1.00) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL9690927 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL1421341 | 0.80 | TDP1 (1.00) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL9000125 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL28470699 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995021-A | DIAZOTIZATION OF AN AMINO PHENYL SUBSTITUTED HAPTEN | BIOLOGICAL DEVELOPMENTS, INC. (US) | 1976-11-30 | — | — | US | claimed |
| CN-103044336-B | Acylthiourea compound, preparation method and application thereof | UNIV CHINA AGRICULTURAL | 2014-11-19 | — | — | CN | disclosed |
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| EP-0090240-A2 | 7-Alpha-aminoacyl-3-chlorocephalosporins, their preparation and their use as pharmaceutical products | BAYER AG (DE) | 1983-10-05 | — | — | EP | disclosed |
| EP-0011092-A1 | Alpha-aminophenylacetic acid derivatives for use in the treatment of inflammations and novel alpha-aminophenylacetic acid derivatives | BAYER AG (DE) | 1980-05-28 | — | — | EP | disclosed |