Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470699 | 1.00 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL13527924 | 0.89 | TDP1 (0.80) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL12157332 | 0.83 | ESR2 (0.47) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL7167731 | 0.82 | TDP1 (0.69) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL11415027 | 0.81 | TDP1 (0.47) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL28916331 | 0.81 | GUSB (0.50) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL9000125 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL9690927 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL8270572 | 0.80 | TDP1 (1.00) | TDP1ALDH1A1MAPTLMNAGAA | |
| SCHEMBL8252775 | 0.80 | TDP1 (0.67) | TDP1ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117816204-B | Floating catalyst and application thereof in synthesizing p-hydroxy-phenylhydantoin | TIANJIN VOCATIONAL INSTITUTE (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119707825-A | Crystal form of p-hydroxy phenylhydantoin and preparation method thereof | 合肥菁科生物科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119506370-A | Preparation method of D-p-hydroxyphenylglycine | 上海邦林生物科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-115927274-B | Carbamoyl hydrolase mutants | 上海邦林生物科技有限公司 | 2025-02-07 | — | — | CN | claimed |
| US-20250043323-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES | Enzymaster (Ningbo) Bio-Engineering Co., Ltd (CN) | 2025-02-06 | — | — | US | claimed |
| CN-119041202-B | Antibacterial finishing agent, application method thereof and antibacterial pure cotton towel | 淄博新亚纺织有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-119041202-A | Antibacterial finishing agent, application method thereof and antibacterial pure cotton towel | 淄博新亚纺织有限公司 | 2024-11-29 | — | — | CN | claimed |
| EP-4433602-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF PREGABALIN INTERMEDIATES | Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) | 2024-09-25 | — | — | EP | claimed |
| CN-118667895-A | Improved production process of p-hydroxyphenylglycine by enzyme method | 联邦制药(内蒙古)有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118389483-A | Preparation method and application of carrier-free precipitation crosslinking hybridization nanoflower co-immobilized double-enzyme catalyst | 天津科技大学 | 2024-07-26 | — | — | CN | claimed |
| EP-0437058-A1 | Formation of hydroxyaromatic ketoacetal from an hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and D-p-hydroxyphenylglycine from 4-hydroxyacetophenone | HOECHST CELANESE CORPORATION (US) | 1991-07-17 | — | — | EP | claimed |
| WO-1991009020-A2 | PRODUCTION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-p-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE | HOECHST CELANESE CORPORATION (US) | 1991-06-27 | — | — | WO | claimed |
| US-4440934-A | MICROBIOCIDES | PACIFIC CHEMICAL IND. CO., LTD. (KR) | 1984-04-03 | — | — | US | claimed |
| US-4436877-A | HYDANTOIN TO RETARD EVOLUTION OF AROMATIC DIACID VAPORS DURING MELT PROCESSING | POLYPLASTICS CO., LTD. (JP) | 1984-03-13 | — | — | US | claimed |
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| EP-0008547-B1 | PROCESS FOR THE PREPARATION OF R.S. 5-P-HYDROXYPHENYL-2,4-IMIDAZOLIDINE DIONE OR R.S. 5-P-HYDROXYPHENYL HYDANTOIN | SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) | 1982-11-10 | — | — | EP | claimed |
| US-4230869-A | REACTING PHENOL, UREA AND GLYCOLIC ACID | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1980-10-28 | — | — | US | claimed |
| US-4211840-A | USING ENZYME SPECIFIC FOR D-ISOMER OF 5-SUBSTITUTED HYDANTOIN | AJINOMOTO COMPANY, INCORPORATED (JP) | 1980-07-08 | — | — | US | claimed |
| EP-0001319-A1 | Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained | BEECHAM GROUP PLC (GB) | 1979-04-04 | — | — | EP | claimed |
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | claimed |