Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | CYBB | P04839 | 1/20 | 0.45 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.45 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GALR2 | O43603 | 3/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246394 | 0.94 | MAPT (0.57) | LMNAMAPTCYBBNOX5NOX3 | |
| SCHEMBL8254136 | 0.89 | CYBB (0.51) | LMNAMAPTCYBBNOX5NOX3 | |
| SCHEMBL3240269 | 0.89 | LMNA (0.52) | LMNAMAPTCYBBNOX5NOX3 | |
| SCHEMBL8256922 | 0.88 | LMNA (0.47) | LMNAMAPTGALR2GALR1 | |
| SCHEMBL8254234 | 0.88 | MAPT (0.47) | LMNAMAPTPOLBNPSR1GALR2 | |
| SCHEMBL8247655 | 0.85 | GALR2 (0.40) | LMNAMAPTPOLBNPSR1GALR2 | |
| SCHEMBL3242771 | 0.84 | LMNA (0.49) | LMNAMAPTCYBBNOX5NOX3 | |
| SCHEMBL8256912 | 0.84 | EGFR (0.43) | LMNAMAPTPOLBNPSR1GALR2 | |
| SCHEMBL8253195 | 0.83 | MAPT (0.48) | LMNAMAPTCYBBNOX5NOX3 | |
| SCHEMBL8253262 | 0.83 | MAPT (0.44) | LMNAMAPTCYBBNOX4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | GALR3, GALR2, GALR1 | LMNA 3975/4885MAPT 2638/4885CYBB 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.