Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475379 | 0.85 | BCL2L1 (0.54) | TTRBCL2L1BADNFE2L2SRD5A1 | |
| SCHEMBL10804476 | 0.85 | BCL2L1 (0.54) | TTRBCL2L1BADNFE2L2SRD5A1 | |
| SCHEMBL9797931 | 0.84 | GRIK1 (0.55) | TTRBCL2L1BADMAOAMAOB | |
| SCHEMBL10496436 | 0.84 | GRIK1 (0.55) | TTRBCL2L1BADMAOAMAOB | |
| SCHEMBL12062910 | 0.83 | BCL2L1 (0.50) | TTRBCL2L1BADSRD5A1SRD5A2 | |
| SCHEMBL8257425 | 0.83 | BCL2L1 (0.50) | TTRBCL2L1BADSRD5A1SRD5A2 | |
| SCHEMBL11687899 | 0.82 | NFE2L2 (0.55) | MAOAMAOBNFE2L2RELA | |
| SCHEMBL11687908 | 0.82 | NFE2L2 (0.55) | MAOAMAOBNFE2L2RELA | |
| SCHEMBL4138829 | 0.79 | BCL2L1 (0.49) | TTRBCL2L1BADMAOAMAOB | |
| SCHEMBL9095657 | 0.76 | TTR (0.59) | TTRBCL2L1BADSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116157-A2 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2006-11-02 | — | — | WO | disclosed |