Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8254385 | 1.00 | MAPT (0.42) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL12052148 | 1.00 | MAPT (0.42) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL4734654 | 0.86 | RXRA (0.47) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL25941561 | 0.83 | PTGS1 (0.42) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL12052133 | 0.80 | PARP1 (0.55) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL8249965 | 0.80 | PARP1 (0.55) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL7613565 | 0.80 | ANPEP (0.64) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL8255364 | 0.80 | PARP1 (0.55) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL7613619 | 0.80 | ANPEP (0.64) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL505969 | 0.80 | ANPEP (0.64) | MAPTPTGS1CXCR1CXCR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116157-A9 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS INC (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2006116157-A2 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2006-11-02 | — | — | WO | disclosed |