Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | HCK | P08631 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265827 | 0.86 | HPGD (0.52) | KDM4EHPGDPPARGNR2E3NCOR2 | |
| SCHEMBL2035227 | 0.86 | ADK (0.41) | KDM4EHPGDPPARGNR2E3NCOR2 | |
| SCHEMBL2034210 | 0.85 | ADK (0.48) | KDM4EHPGDADKKMT2AMEN1 | |
| SCHEMBL8267956 | 0.84 | HPGD (0.43) | KDM4EHPGDPPARGNR2E3NCOR2 | |
| SCHEMBL2035054 | 0.84 | ADK (0.38) | KDM4EHPGDPPARGNR2E3NCOR2 | |
| SCHEMBL8254635 | 0.84 | ADK (0.42) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL8215356 | 0.84 | PI4KA (0.36) | PI4KBKDM4EHPGDPPARGNR2E3 | |
| SCHEMBL2042387 | 0.82 | GSK3B (0.41) | KDM4EHPGDPPARGNR2E3NCOR2 | |
| SCHEMBL8147918 | 0.81 | KDM4E (0.35) | KDM4EHPGDPPARGNR2E3NCOR2 | |
| SCHEMBL8214439 | 0.81 | PRKD3 (0.40) | KDM4EHPGDPPARGNR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |