Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488570 | 0.86 | NR1H2 (0.42) | NR1H2NR1H3PTPN1HSD17B10EPHX2 | |
| SCHEMBL18084469 | 0.86 | NR1H2 (0.42) | NR1H2NR1H3PTPN1HSD17B10EPHX2 | |
| SCHEMBL883144 | 0.85 | PTPN1 (0.40) | NR1H2NR1H3PTPN1HSD17B10EPHX2 | |
| SCHEMBL9003564 | 0.85 | HSD17B10 (0.46) | NR1H2NR1H3HSD17B10EPHX2SMN1; SMN2 | |
| SCHEMBL8337366 | 0.85 | PTPN1 (0.40) | NR1H2NR1H3PTPN1HSD17B10EPHX2 | |
| SCHEMBL30987635 | 0.85 | PTPN1 (0.40) | NR1H2NR1H3PTPN1HSD17B10EPHX2 | |
| SCHEMBL30396554 | 0.85 | HSD17B10 (0.46) | NR1H2NR1H3HSD17B10EPHX2SMN1; SMN2 | |
| SCHEMBL10269862 | 0.84 | NR1H2 (0.41) | NR1H2NR1H3PTPN1HSD17B10EPHX2 | |
| SCHEMBL2127763 | 0.84 | NR1H2 (0.41) | NR1H2NR1H3PTPN1HSD17B10EPHX2 | |
| SCHEMBL30272143 | 0.84 | NR1H2 (0.41) | NR1H2NR1H3PTPN1HSD17B10EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116157-A9 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS INC (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2006116157-A2 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2006-11-02 | — | — | WO | disclosed |