Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.59 |
| ▸ | PARP1 | P09874 | 6/20 | 0.59 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 6/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162850 | 0.87 | PARP10 (0.63) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL21335655 | 0.83 | PARP10 (0.58) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL14984344 | 0.81 | PARP10 (0.58) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL22995086 | 0.81 | PARP10 (0.63) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL8190887 | 0.80 | PARP10 (0.58) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL27445552 | 0.79 | PARP11 (0.52) | PARP10PARP1PARP11PDPK1HTR2C | |
| SCHEMBL12464716 | 0.78 | PARP10 (0.51) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL8688671 | 0.77 | PBRM1 (0.50) | CNR1CNR2HTR2CHTR2BHTR2A | |
| SCHEMBL4190017 | 0.77 | SMN1; SMN2 (0.51) | PARP10PARP1CNR1CNR2HTR2C | |
| SCHEMBL2619126 | 0.75 | PARP10 (1.00) | PARP10PARP1F7F3PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |