Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | GRB2 | P62993 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249934 | 0.95 | NPSR1 (0.43) | NPSR1DPP4DPP8DPP7DPP9 | |
| SCHEMBL8246705 | 0.90 | DPP4 (0.43) | NPSR1DPP4DPP8DPP7DPP9 | |
| SCHEMBL8249847 | 0.90 | NPSR1 (0.39) | NPSR1DPP4DPP8DPP7DPP9 | |
| SCHEMBL8247400 | 0.85 | DPP4 (0.41) | NPSR1DPP4DPP8DPP7DPP9 | |
| SCHEMBL8248226 | 0.84 | DPP4 (0.38) | NPSR1DPP4DPP8DPP7DPP9 | |
| SCHEMBL8250093 | 0.82 | NPSR1 (0.39) | NPSR1DPP4DPP8DPP7DPP9 | |
| SCHEMBL8249374 | 0.82 | DPP4 (0.41) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8250760 | 0.79 | NPSR1 (0.38) | NPSR1FKBP5FKBP1AF2CTSK | |
| SCHEMBL12605913 | 0.79 | DPP4 (0.39) | NPSR1DPP4DPP8DPP7DPP9 | |
| SCHEMBL12601475 | 0.77 | ELANE (0.39) | F2CTSKGRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130687-A2 | LIVER/PLASMA CONCENTRATION RATIO FOR DOSING HEPATITIS C VIRUS PROTEASE INHIBITOR | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |