Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247400 | 0.94 | DPP4 (0.41) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8253477 | 0.90 | DPP4 (0.38) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8247918 | 0.90 | DPP4 (0.38) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12601475 | 0.88 | ELANE (0.39) | GRB2F2ELANECTSK | |
| SCHEMBL8249934 | 0.86 | NPSR1 (0.43) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8243897 | 0.84 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8280370 | 0.84 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12601319 | 0.83 | DPP4 (0.45) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8255656 | 0.82 | NPSR1 (0.44) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12606135 | 0.80 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130553-A2 | HCV PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006130626-A2 | METHOD FOR MODULATING ACTIVITY OF HCV PROTEASE THROUGH USE OF A NOVEL HCV PROTEASE INHIBITOR TO REDUCE DURATION OF TREATMENT PERIOD | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006130627-A2 | METHODS FOR TREATING HEPATITIS C | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |