Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10165783 | 0.90 | MMP13 (0.46) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL14451096 | 0.87 | MMP13 (0.45) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL8253193 | 0.86 | MMP13 (0.43) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL10166131 | 0.86 | MMP13 (0.46) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL8247180 | 0.86 | MMP13 (0.43) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL8255825 | 0.84 | MMP13 (0.67) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL8256464 | 0.84 | MMP13 (0.60) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL10161793 | 0.84 | MMP13 (0.60) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL8254325 | 0.83 | MMP13 (0.58) | MMP13ADAMTS4MMP3MMP8MMP12 | |
| SCHEMBL8253336 | 0.81 | MMP13 (0.49) | MMP13ADAMTS4MMP3MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |