Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
| ▸ | CCKBR | P32239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25862215 | 0.90 | GLP1R (0.59) | GLP1RCCKARCCKBR | |
| SCHEMBL25462505 | 0.89 | GLP1R (0.45) | GLP1RFOLH1 | |
| SCHEMBL27342282 | 0.89 | GLP1R (0.45) | GLP1RFOLH1 | |
| SCHEMBL27343320 | 0.89 | GLP1R (0.61) | GLP1RFOLH1 | |
| SCHEMBL27343704 | 0.84 | GLP1R (0.51) | GLP1RFOLH1CCKARCCKBR | |
| SCHEMBL71109 | 0.82 | GLP1R (0.57) | GLP1RFOLH1CCKARCCKBR | |
| SCHEMBL20993544 | 0.82 | GLP1R (0.50) | GLP1RFOLH1 | |
| SCHEMBL72060 | 0.82 | GLP1R (0.57) | GLP1RFOLH1CCKARCCKBR | |
| SCHEMBL71091 | 0.82 | GLP1R (0.57) | GLP1RFOLH1CCKARCCKBR | |
| SCHEMBL24920301 | 0.81 | GLP1R (0.45) | GLP1RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322546-A1 | Acylated GLP-1 compounds | NOVO NORDISK A/S (DK) | 2011-05-18 | — | — | EP | disclosed |
| WO-2006097537-A2 | ACYLATED GLP-1 COMPOUNDS | NOVO NORDISK A/S (DK) | 2006-09-21 | — | — | WO | disclosed |
| WO-2006097538-A1 | EXTENDED GLP-1 COMPOUNDS | NOVO NORDISK A/S (DK) | 2006-09-21 | — | — | WO | disclosed |