⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757980 | 1.00 | — | — | |
| SCHEMBL6883369 | 1.00 | — | — | |
| SCHEMBL6757966 | 1.00 | — | — | |
| SCHEMBL6758020 | 1.00 | — | — | |
| SCHEMBL6884434 | 1.00 | — | — | |
| SCHEMBL6758012 | 1.00 | — | — | |
| Bicarbonate SCHEMBL11291705 | 0.88 | TRPA1 (0.44) | — | |
| SCHEMBL11376568 | 0.84 | — | — | |
| SCHEMBL5868611 | 0.84 | — | — | |
| (-)-(1S,3R,4S,6S)-6-Hydroxymenthol SCHEMBL7043768 | 0.84 | TRPA1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12391802-B2 | Method of forming semicrystalline polyetherimide, and polyetherimide-containing composition | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2025-08-19 | — | — | US | disclosed |
| US-20230374035-A1 | RAS INHIBITORS | Revolution Medicines, Inc. | 2023-11-23 | — | — | US | disclosed |
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| US-20230226186-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-20 | — | — | US | disclosed |
| US-11690915-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20220162387-A1 | METHOD OF FORMING SEMICRYSTALLINE POLYETHERIMIDE, AND POLYETHERIMIDECONTAINING COMPOSITION | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2022-05-26 | — | — | US | disclosed |
| CN-113748155-A | Methods of forming semi-crystalline polyetherimides and compositions comprising polyetherimides | 高新特殊工程塑料全球技术有限公司 | 2021-12-03 | — | — | CN | disclosed |
| WO-2020234683-A1 | METHOD OF FORMING SEMICRYSTALLINE POLYETHERIMIDE, AND POLYETHERIMIDE-CONTAINING COMPOSITION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-11-26 | — | — | WO | disclosed |
| EP-3741792-A1 | METHOD OF FORMING SEMICRYSTALLINE POLYETHERIMIDE, AND POLYETHERIMIDE-CONTAINING COMPOSITION | SABIC Global Technologies B.V. (NL) | 2020-11-25 | — | — | EP | disclosed |
| WO-2020193649-A1 | NEW THERAPEUTIC APPLICATION OF 1,2-DIOXOLANE-3,5-DISUBSTITUTED COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF | Universite Paris-Saclay (FR) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020193650-A1 | PROCESS FOR PREPARING 1,2-ENDOPEROXIDE COMPOUNDS | Universite Paris-Saclay (FR) | 2020-10-01 | — | — | WO | disclosed |
| US-7312334-B2 | Method of preparing inhibitors phosphodiesterase-4 | MERCK & CO. INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20040102472-A1 | Method of preparing inhibitors of phosphodiesterase-4 | MERCK & CO., INC. | 2004-05-27 | — | — | US | disclosed |