Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2445340 | 0.89 | MEN1 (0.52) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2688487 | 0.89 | MEN1 (0.52) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2445342 | 0.89 | MEN1 (0.52) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL14275818 | 0.85 | ALDH1A1 (0.54) | MEN1TP53KMT2ASMN1; SMN2AKR1C3 | |
| SCHEMBL3649014 | 0.83 | MEN1 (0.57) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13212656 | 0.81 | MEN1 (0.60) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2437206 | 0.80 | MEN1 (0.57) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL14275572 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2A | |
| SCHEMBL16238599 | 0.78 | MEN1 (0.56) | MEN1TP53KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13850112 | 0.78 | HSD17B10 (0.57) | KMT2ASMN1; SMN2MAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006111549-A1 | DIHYDROTHIENOPYRIMIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-10-26 | — | — | WO | disclosed |