Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247831 | 0.72 | HDAC1 (0.53) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL5995076 | 0.69 | HDAC1 (0.48) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL5995067 | 0.69 | HDAC1 (0.48) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL8256893 | 0.68 | HDAC1 (0.48) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL15304138 | 0.68 | HDAC1 (1.00) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL13140098 | 0.67 | HDAC1 (0.59) | HDAC1HDAC8HDAC6HDAC2HDAC11 | |
| SCHEMBL19184613 | 0.66 | HDAC1 (0.88) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL14582625 | 0.66 | HDAC1 (0.95) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL13118161 | 0.66 | HDAC1 (0.77) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL5994507 | 0.66 | HDAC1 (0.46) | HDAC1HDAC8HDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101456-A1 | BICYCLIC HETEROCYCLES HYDROXAMATE COMPOUNDS USEFUL AS HISTONE DEACETYLASE (HDAC) INHIBITORS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |