Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27047963 | 0.87 | SYK (0.46) | SYKAAK1SSTR4PDPK1CYP17A1 | |
| SCHEMBL13302742 | 0.86 | SYK (0.43) | SYKAAK1SSTR4PDPK1CYP17A1 | |
| SCHEMBL8258382 | 0.86 | LOXL2 (0.42) | SYKSSTR4 | |
| SCHEMBL959129 | 0.86 | SYK (0.41) | SYKAAK1SSTR4PDPK1CYP17A1 | |
| SCHEMBL13302725 | 0.86 | SYK (0.41) | SYKAAK1SSTR4PDPK1CYP17A1 | |
| SCHEMBL13302714 | 0.85 | SYK (0.43) | SYKAAK1SSTR4PDPK1CYP17A1 | |
| SCHEMBL13302743 | 0.83 | SYK (0.39) | SYKAAK1SSTR4PDPK1USP30 | |
| SCHEMBL21999429 | 0.81 | SYK (0.40) | SYKAAK1SSTR4PDPK1SMN1; SMN2 | |
| SCHEMBL14510524 | 0.80 | SYK (0.40) | SYKAAK1SSTR4PDPK1 | |
| SCHEMBL3335527 | 0.80 | NPC1 (0.49) | SYKAAK1SSTR4PDPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |