Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176944 | 0.82 | TSHR (0.41) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL14860226 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL8386034 | 0.80 | ELANE (0.33) | TSHR | |
| SCHEMBL1739273 | 0.76 | TSHR (0.44) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL8731397 | 0.75 | — | — | |
| SCHEMBL3064100 | 0.75 | — | — | |
| SCHEMBL14041325 | 0.75 | — | — | |
| SCHEMBL22661001 | 0.75 | TSHR (0.36) | TSHRTDP1 | |
| SCHEMBL6368022 | 0.73 | — | — | |
| SCHEMBL20838323 | 0.73 | TSHR (0.46) | TSHRCHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585498-B1 | QUATERNIZED COPOLYMER | BASF SE (DE) | 2018-05-30 | — | — | EP | disclosed |
| EP-2585498-A1 | QUATERNIZED COPOLYMER | BASF SE (DE) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011161149-A1 | QUATERNIZED COPOLYMER | BASF SE (DE) | 2011-12-29 | — | — | WO | disclosed |
| EP-0307815-B1 | FUELS FOR SPARK IGNITION ENGINES | BASF Aktiengesellschaft (DE) | 1992-04-08 | — | — | EP | disclosed |
| EP-0307815-A1 | Fuels for spark ignition engines | BASF Aktiengesellschaft (DE) | 1989-03-22 | — | — | EP | disclosed |