Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240043 | 0.97 | F2 (0.39) | F2F10DPP4DPP8DPP7 | |
| SCHEMBL12605913 | 0.89 | DPP4 (0.39) | F2DPP4DPP8DPP7DPP9 | |
| SCHEMBL8248226 | 0.88 | DPP4 (0.38) | F2F10DPP4DPP8DPP7 | |
| SCHEMBL8280667 | 0.87 | F2 (0.38) | F2F10DPP4OPRM1ALDH1A1 | |
| SCHEMBL8249847 | 0.86 | NPSR1 (0.39) | F2F10DPP4DPP8DPP7 | |
| SCHEMBL12600611 | 0.86 | DPP4 (0.38) | F2DPP4DPP8DPP7DPP9 | |
| SCHEMBL8251047 | 0.85 | DPP4 (0.45) | F2F10DPP4DPP8DPP7 | |
| SCHEMBL8240265 | 0.85 | DPP4 (0.39) | F2F10DPP4DPP8DPP7 | |
| SCHEMBL8246145 | 0.84 | DPP4 (0.42) | F2F10DPP4DPP8DPP7 | |
| SCHEMBL8244610 | 0.83 | ELANE (0.39) | F2F10DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130686-A2 | HCV PROTEASE INHIBITORS IN COMBINATION WITH FOOD | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |