Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 7/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257927 | 0.87 | F2 (0.39) | F2F10PRSS1XIAPDPP4 | |
| SCHEMBL16329140 | 0.85 | KMT2A (0.39) | F2F10PRSS1 | |
| SCHEMBL12605984 | 0.85 | KMT2A (0.39) | F2F10PRSS1 | |
| SCHEMBL8240043 | 0.85 | F2 (0.39) | F2F10BIRC2DPP4ALDH1A1 | |
| SCHEMBL16313079 | 0.83 | ALDH1A1 (0.32) | DPP4ALDH1A1NPSR1 | |
| SCHEMBL8253163 | 0.82 | F2 (0.33) | F2F10BIRC2PLATPRSS1 | |
| SCHEMBL8247775 | 0.82 | ABCG2 (0.37) | — | |
| SCHEMBL8246486 | 0.82 | — | — | |
| SCHEMBL8250187 | 0.80 | BIRC2 (0.34) | F2F10BIRC2PLATPRSS1 | |
| SCHEMBL12606095 | 0.80 | NPSR1 (0.40) | F2F10BIRC2PLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087731-A1 | SULFUR COMPOUNDS AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2005-09-22 | — | — | WO | disclosed |