Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259358 | 0.87 | HTT (0.56) | HTTIDO1KDM4ELMNAMAPT | |
| SCHEMBL13336667 | 0.79 | HTT (0.51) | HTTKDM4EMAPTMAPK1ALDH1A1 | |
| SCHEMBL8252739 | 0.78 | IDO1 (0.57) | HTTIDO1KDM4ELMNAMAPT | |
| SCHEMBL8449509 | 0.75 | HTT (0.54) | HTTKDM4ELMNAMAPK1ALDH1A1 | |
| SCHEMBL11664169 | 0.75 | HTT (0.54) | HTTKDM4EMAPK1SMN1; SMN2PARP1 | |
| SCHEMBL5362778 | 0.75 | HTT (0.71) | HTTKDM4ELMNAMAPTALDH1A1 | |
| 1,2-Diisopentoxybenzene SCHEMBL2843498 | 0.75 | HTT (0.62) | HTTIDO1KDM4ELMNAMAPT | |
| SCHEMBL11098396 | 0.74 | HTT (0.57) | HTTKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL28416661 | 0.74 | L3MBTL1 (0.68) | HTTKDM4ELMNAMAPTMAPK1 | |
| SCHEMBL12545620 | 0.73 | KMT2A (0.58) | HTTKDM4ELMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2199300-A2 | Peptidic compounds | The University Of Wollongong (AU) | 2010-06-23 | — | — | EP | disclosed |
| WO-2006074501-A1 | PEPTIDIC COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2006-07-20 | — | — | WO | disclosed |