Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.38 |
| ▸ | RORC | P51449 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534720 | 1.00 | REN (0.38) | RENRORCTSHRKMT2A | |
| SCHEMBL2684845 | 0.95 | REN (0.39) | RENRORCTSHRKMT2A | |
| SCHEMBL8471463 | 0.95 | REN (0.42) | RENRORCKMT2A | |
| SCHEMBL2683202 | 0.95 | REN (0.42) | RENRORCKMT2A | |
| SCHEMBL8234737 | 0.94 | REN (0.42) | RENRORC | |
| SCHEMBL3906372 | 0.94 | REN (0.40) | RENRORC | |
| SCHEMBL3906351 | 0.94 | REN (0.42) | RENRORC | |
| SCHEMBL13678856 | 0.94 | REN (0.38) | RENRORCTSHRKMT2A | |
| SCHEMBL2684091 | 0.93 | REN (0.37) | RENRORCKMT2A | |
| SCHEMBL2684089 | 0.90 | REN (0.34) | RENRORCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103275-A1 | 3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2006-10-05 | — | — | WO | disclosed |