Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NECTIN4 | Q96NY8 | 5/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.39 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301056 | 0.96 | CTSL (0.60) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8260113 | 0.95 | CTSL (0.64) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14300848 | 0.95 | CTSL (0.59) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8260125 | 0.94 | CTSL (0.59) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14301032 | 0.94 | CTSL (0.63) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274668 | 0.93 | CTSL (0.67) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274677 | 0.93 | CTSL (0.63) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14275196 | 0.93 | CTSL (0.63) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274667 | 0.93 | CTSL (0.63) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14274902 | 0.91 | CTSL (0.63) | CTSLDRD1PTGS1PDE4AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110185-A2 | ANTIINFECTIVE LIPOPEPTIDES | CUBIST PHARMACEUTICALS, INC. (US) | 2006-10-19 | — | — | WO | disclosed |