Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252441 | 0.90 | HDAC1 (0.61) | HDAC1SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL5808215 | 0.89 | HDAC1 (0.60) | HDAC1MGLLSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8252444 | 0.87 | HDAC1 (0.57) | HDAC1MGLLSMN1; SMN2LMNAGAA | |
| SCHEMBL3573597 | 0.85 | MGLL (0.48) | HDAC1MGLLSMN1; SMN2LMNAGAA | |
| SCHEMBL5805598 | 0.83 | HDAC1 (0.56) | HDAC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1885843 | 0.81 | HDAC1 (0.55) | HDAC1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1886192 | 0.80 | HDAC1 (0.60) | HDAC1MGLLSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3975883 | 0.78 | HDAC1 (0.57) | HDAC1 | |
| SCHEMBL1892705 | 0.78 | HDAC1 (0.57) | HDAC1SMN1; SMN2LMNAGAAATM | |
| SCHEMBL5810656 | 0.77 | HDAC1 (0.66) | HDAC1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |