Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825520 | 0.82 | ALDH1A1 (0.47) | NPSR1MAPTALDH1A1MAOAMAOB | |
| SCHEMBL27297982 | 0.72 | MAPT (0.40) | NPSR1MAPTALDH1A1GAALMNA | |
| SCHEMBL25624811 | 0.71 | MAPT (0.45) | NPSR1MAPTALDH1A1GAAMAOA | |
| SCHEMBL479130 | 0.69 | KCNH2 (0.32) | ALDH1A1LTA4H | |
| SCHEMBL31614318 | 0.69 | MAPT (0.39) | NPSR1MAPTALDH1A1GAAMAOA | |
| SCHEMBL10359187 | 0.69 | MAPT (0.44) | NPSR1MAPTALDH1A1MAOAMAOB | |
| SCHEMBL3708781 | 0.68 | MAPT (0.38) | NPSR1MAPTALDH1A1GAAMAOA | |
| SCHEMBL29901837 | 0.68 | ALDH1A1 (0.48) | MAPTALDH1A1MAOAMAOBLMNA | |
| SCHEMBL22716531 | 0.67 | TSHR (0.54) | NPSR1MAPTGAALMNAL3MBTL1 | |
| SCHEMBL825908 | 0.67 | MAPT (0.44) | NPSR1MAPTALDH1A1GAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157970-A1 | SILYLATED POLYURETHANES | Huntsman International LLC (US) | 2017-04-26 | — | — | EP | claimed |
| WO-2015193146-A1 | SILYLATED POLYURETHANES | HUNTSMAN INTERNATIONAL LLC (US) | 2015-12-23 | — | — | WO | claimed |
| EP-2582737-A1 | ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS | Huntsman International LLC (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011161011-A1 | ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS | HUNTSMAN INTERNATIONAL LLC (US) | 2011-12-29 | — | — | WO | disclosed |
| WO-2005019296-A1 | THERMOPLASTIC POLYURETHANE CONTAINING SILANE GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-03 | — | — | WO | disclosed |