Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12762287 | 0.88 | CYP2D6 (0.34) | TSHRCYP2D6CYP2C19HIF1AGABRR1 | |
| SCHEMBL10065504 | 0.88 | CYP2D6 (0.34) | TSHRCYP2D6CYP2C19HIF1AGABRR1 | |
| SCHEMBL12363478 | 0.88 | CYP2D6 (0.34) | TSHRCYP2D6CYP2C19HIF1AGABRR1 | |
| SCHEMBL29054985 | 0.83 | CYP2D6 (0.39) | TSHRCYP2D6CYP2C19HIF1AGABRR1 | |
| SCHEMBL1716424 | 0.82 | CYP2C19 (0.42) | TSHRCYP2D6CYP2C19HIF1ACYP1A2 | |
| SCHEMBL3751590 | 0.82 | CYP2D6 (0.35) | TSHRCYP2D6CYP2C19HIF1AGABRR1 | |
| SCHEMBL15711664 | 0.82 | MMP8 (0.35) | GABRR1CYP1A2ACE2FOLH1NAALAD2 | |
| SCHEMBL27941875 | 0.81 | CYP2D6 (0.60) | TSHRCYP2D6CYP2C19HIF1AGABRR1 | |
| SCHEMBL13645728 | 0.80 | CA1 (0.35) | TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL13252739 | 0.80 | MMP8 (0.38) | TSHRCYP2D6CYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323151-A1 | IMIDE ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2023-10-12 | — | — | US | disclosed |
| US-20110294053-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-12-01 | — | — | US | disclosed |
| EP-2368908-A2 | Anti- angiogenic compounds | CovX Technologies Ireland Limited (IE) | 2011-09-28 | — | — | EP | disclosed |
| EP-2292248-A2 | Anti-angiogenic compounds | CovX Technologies Ireland Limited (IE) | 2011-03-09 | — | — | EP | disclosed |
| EP-2147684-A1 | Diagnostic Agents Selective Against Metalloproteases | Bracco Imaging S.p.A (IT) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008081418-A1 | GLUCAGON-LIKE PROTEIN-1 RECEPTOR (GLP-1R) AGONIST COMPOUNDS | COVX TECHNOLOGIES IRELAND LIMITED (IE) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008056346-A2 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND LIMITED (IE) | 2008-05-15 | — | — | WO | disclosed |
| WO-2006095234-A2 | INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO IMAGING S.P.A. (IT) | 2006-09-14 | — | — | WO | disclosed |