SCHEMBL8259175

SCHEMBL8259175

COCCCOc1cc(CC(C[C@H](N)C(O)CC(C(=O)NC2CCOCC2)C(C)C)C(C)C)ccc1C

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427859 1.00 REN (0.61) REN
SCHEMBL427814 0.92 REN (0.71) REN
SCHEMBL8254954 0.92 REN (0.60) REN
SCHEMBL14129461 0.92 REN (0.60) REN
SCHEMBL14097929 0.92 REN (0.60) REN
SCHEMBL4679071 0.92 REN (0.60) REN
SCHEMBL14097968 0.92 REN (0.60) REN
SCHEMBL8258892 0.92 REN (0.60) REN
SCHEMBL14129512 0.92 REN (0.60) REN
SCHEMBL14129475 0.92 REN (0.60) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006095020-A1 HETEROCYCLIC-SUBSTITUTED ALKANAMIDES USEFUL AS RENIN INHIBITORS SPEEDEL EXPERIMENTA AG (CH) 2006-09-14 WO disclosed