Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581948 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| SCHEMBL30537960 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| SCHEMBL3827353 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| SCHEMBL5471209 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| Hydrochloric Acid SCHEMBL1465100 | 0.98 | DPP4 (0.42) | DPP4DPP9DPP8GLI1SMYD3 | |
| Hydrochloric Acid SCHEMBL1464735 | 0.98 | DPP4 (0.42) | DPP4DPP9DPP8GLI1SMYD3 | |
| Hydrochloric Acid SCHEMBL4208729 | 0.98 | DPP4 (0.42) | DPP4DPP9DPP8GLI1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL2496511 | 0.88 | DPP4 (0.37) | DPP4DPP9DPP8GLI1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL2494834 | 0.88 | DPP4 (0.37) | DPP4DPP9DPP8GLI1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL2497613 | 0.88 | DPP4 (0.37) | DPP4DPP9DPP8GLI1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605798-A | Imidazothiazole derivative | DAIICHI SANKYO CO LTD (JP) | 2009-12-16 | — | — | CN | disclosed |
| WO-2006100082-A2 | SUBSTITUTED OXINDOL DERIVATIVES, DRUGS CONTAINING SAID DERIVATIVES AND THE USE THEREOF | ABBOTT GMBH & CO. KG (DE) | 2006-09-28 | — | — | WO | disclosed |