Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30537960 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| SCHEMBL8259677 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| SCHEMBL3827353 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| SCHEMBL5471209 | 1.00 | DPP4 (0.44) | DPP4DPP9DPP8GLI1SMYD3 | |
| Hydrochloric Acid SCHEMBL1465100 | 0.98 | DPP4 (0.42) | DPP4DPP9DPP8GLI1SMYD3 | |
| Hydrochloric Acid SCHEMBL1464735 | 0.98 | DPP4 (0.42) | DPP4DPP9DPP8GLI1SMYD3 | |
| Hydrochloric Acid SCHEMBL4208729 | 0.98 | DPP4 (0.42) | DPP4DPP9DPP8GLI1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL2496511 | 0.88 | DPP4 (0.37) | DPP4DPP9DPP8GLI1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL2494834 | 0.88 | DPP4 (0.37) | DPP4DPP9DPP8GLI1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL2497613 | 0.88 | DPP4 (0.37) | DPP4DPP9DPP8GLI1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743176-A1 | DEUTERATED 1,3 DIHYDRO -2H-INDOLE-2-ONE DERIVATIVES | HMNC Holding GmbH (DE) | 2026-05-20 | — | — | EP | disclosed |
| US-20250034117-A1 | Deuterated 1,3 Dihydro -2H-indole-2-one derivatives | HMNC Holding GmbH (DE) | 2025-01-30 | — | — | US | disclosed |
| WO-2025012460-A1 | DEUTERATED 1,3 DIHYDRO -2H-INDOLE-2-ONE DERIVATIVES | HMNC Holding GmbH (DE) | 2025-01-16 | — | — | WO | disclosed |
| CN-101033209-B | Method of preparing pharmaceutical intermediate of (2S,4R)-4-hydroxy-N,N-dimethyl-2-pyrrolidineformamide | SHANGHAI INST PHARM INDUSTRY | 2014-08-27 | — | — | CN | disclosed |
| CN-101033209-A | Method of preparing pharmaceutical intermediate of (2S,4R)-4-hydroxy-N,N-dimethyl-2-pyrrolidineformamide | SHANGHAI INST PHARM INDUSTRY (CN) | 2007-09-12 | — | — | CN | disclosed |
| EP-1255751-B1 | 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES AND THEIR USE AS LIGANDS FOR V1B OR V1B AND V1A ARGININE-VASOPRESSIN RECEPTORS | SANOFI SYNTHELABO (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1255751-A2 | 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES AND THEIR USE AS LIGANDS FOR V1B OR V1B AND V1A ARGININE-VASOPRESSIN RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001055130-A2 | NOVEL 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVES AND THEIR USE AS LIGANDS FOR V1B AND V1A ARGININE-VASOPRESSIN RECEPTORS | SANOFI-SYNTHELABO (FR) | 2001-08-02 | — | — | WO | disclosed |
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5093328-A | Carbapenicillin antibiotics | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |
| EP-0243686-A2 | Beta-lactam compounds, and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034117-A1 | Deuterated 1,3 Dihydro -2H-indole-2-one derivatives | IDO1, IDO2, TPH1 | DPP4 492/4885DPP9 1245/4885DPP8 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.