SCHEMBL826006

SCHEMBL826006

Nc1ccc(N(CCO)CCO)cc1CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
S100B P04271 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.36
MCL1 Q07820 1/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
MMP14 P50281 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27494177 0.87 MAPT (0.39) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL6429126 0.86 TDP1 (0.39) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL5348348 0.86 S100B (0.43) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL16815119 0.82 KMT2A (0.42) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL6311357 0.82 KMT2A (0.35) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL11443253 0.81 S100B (0.59) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL8061571 0.80 S100B (0.49) KMT2AMAPTMEN1S100BTDP1
SCHEMBL27498414 0.78 S100B (0.47) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL14713525 0.78 KMT2A (0.40) KMT2AMAPTMEN1LMNASMN1; SMN2
SCHEMBL30491146 0.78 S100B (0.65) KMT2AMAPTMEN1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211379-B2 Test strip with slot vent opening ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2012-07-03 US disclosed
US-8142721-B2 Test strip with slot vent opening ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2012-03-27 US disclosed
US-8119414-B2 Test strip with slot vent opening ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2012-02-21 US disclosed
US-20120009095-A1 TEST STRIP WITH SLOT VENT OPENING ROCHE DIABETES CARE, INC. 2012-01-12 US disclosed
US-20110011738-A1 TEST STRIP WITH SLOT VENT OPENING ROCHE DIABETES CARE, INC. 2011-01-20 US disclosed
US-20110000610-A1 TEST STRIP WITH SLOT VENT OPENING ROCHE DIABETES CARE, INC. 2011-01-06 US disclosed