Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | KCNB1 | Q14721 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033015 | 0.79 | ABL1 (0.47) | ABL1CHEK2PORCNPTGDR2ENPP3 | |
| SCHEMBL5030575 | 0.74 | KCNB1 (0.52) | ABL1CHEK2PORCNPTGDR2F2 | |
| SCHEMBL5030737 | 0.74 | ADORA2A (0.51) | ABL1CHEK2PORCNPTGDR2MAPK14 | |
| SCHEMBL5031519 | 0.72 | ADORA2A (0.53) | ABL1PORCNPTGDR2MAPK14 | |
| SCHEMBL8261212 | 0.72 | JAK3 (0.35) | ABL1KDRROCK2PLK4AURKA | |
| SCHEMBL8235803 | 0.72 | ABL1 (0.39) | ABL1CHEK2PORCNPTGDR2ENPP3 | |
| SCHEMBL4724893 | 0.70 | ABL1 (0.44) | ABL1CHEK2PORCNPTGDR2HDAC2 | |
| SCHEMBL4764710 | 0.70 | IL2 (0.58) | ABL1PORCN | |
| SCHEMBL8261109 | 0.69 | LMNA (0.51) | ABL1PORCNPTGDR2F2F10 | |
| SCHEMBL4725014 | 0.69 | IL2 (0.48) | ABL1CHEK2PORCNPTGDR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083477-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-10 | — | — | WO | disclosed |