Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 11/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260168 | 0.92 | IL2 (0.58) | IL2ABL1LRRK2 | |
| SCHEMBL15395851 | 0.87 | IL2 (0.51) | IL2ABL1 | |
| SCHEMBL8259868 | 0.83 | IL2 (0.40) | IL2POLQ | |
| SCHEMBL15395772 | 0.82 | IL2 (0.55) | IL2ABL1 | |
| SCHEMBL5554369 | 0.82 | IL2 (0.51) | IL2ABL1 | |
| SCHEMBL13170837 | 0.81 | ABCB1 (0.43) | WNT3A | |
| SCHEMBL5550529 | 0.80 | IL2 (0.49) | IL2 | |
| SCHEMBL5556181 | 0.79 | IL2 (0.47) | IL2ABL1 | |
| SCHEMBL5555293 | 0.79 | IL2 (0.51) | IL2ABL1 | |
| SCHEMBL8259823 | 0.79 | IL2 (0.46) | IL2ABL1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081391-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-03 | — | — | WO | disclosed |