Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 4/20 | 0.40 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 7/20 | 0.37 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15395989 | 0.89 | IL2 (0.43) | IL2STIM1ORAI1ORAI2F10 | |
| SCHEMBL5554247 | 0.84 | ALDH1A1 (0.48) | IL2STIM1ORAI1ORAI2F10 | |
| SCHEMBL8260575 | 0.83 | IL2 (0.48) | IL2POLQ | |
| SCHEMBL15395770 | 0.83 | IL2 (0.46) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL5550895 | 0.81 | IL2 (0.43) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL13170837 | 0.80 | ABCB1 (0.43) | F10NPC1RAB9AMAPTKLKB1 | |
| SCHEMBL15395851 | 0.80 | IL2 (0.51) | IL2NPC1RAB9AMAPT | |
| SCHEMBL5554346 | 0.79 | IL2 (0.52) | IL2STIM1ORAI1ORAI2SMN1; SMN2 | |
| SCHEMBL5556038 | 0.78 | ALDH1A1 (0.41) | IL2STIM1ORAI1ORAI2F10 | |
| SCHEMBL8260146 | 0.77 | IL2 (0.39) | IL2STIM1ORAI1ORAI2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081391-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-03 | — | — | WO | disclosed |