SCHEMBL8260669

SCHEMBL8260669

COCCCOc1cc(CC(C[C@H](N)C(O)CC(C(=O)NC2CCN(C(C)C)CC2)C(C)C)C(C)C)ccc1OC

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14129590 1.00 REN (0.69) REN
SCHEMBL428859 0.94 REN (0.69) REN
SCHEMBL7305715 0.93 REN (0.68) REN
SCHEMBL14098005 0.93 REN (0.68) REN
SCHEMBL14129473 0.93 REN (0.68) REN
Hydrochloric Acid SCHEMBL7297247 0.93 REN (0.70) REN
SCHEMBL14097998 0.92 REN (0.70) REN
SCHEMBL14098003 0.91 REN (0.69) REN
SCHEMBL14097889 0.91 REN (0.66) REN
SCHEMBL431645 0.91 REN (0.68) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1958666-A1 Heterocyclic-substituted alkanamides as therapeutic compounds Speedel Experimenta AG (CH) 2008-08-20 EP disclosed
WO-2006095020-A1 HETEROCYCLIC-SUBSTITUTED ALKANAMIDES USEFUL AS RENIN INHIBITORS SPEEDEL EXPERIMENTA AG (CH) 2006-09-14 WO disclosed