Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284754 | 1.00 | TP53 (0.44) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3284654 | 0.91 | LMNA (0.45) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3286086 | 0.91 | TP53 (0.44) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3291313 | 0.91 | TP53 (0.42) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3285180 | 0.90 | TP53 (0.45) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3291733 | 0.89 | LMNA (0.44) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL2768223 | 0.88 | TP53 (0.42) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3284382 | 0.88 | TP53 (0.43) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3285196 | 0.88 | LMNA (0.48) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3288361 | 0.87 | TP53 (0.44) | TP53LMNAPOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089909-A1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-08-31 | — | — | WO | disclosed |