Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18088803 | 0.89 | KDM1A (0.44) | KDM1AHDAC9 | |
| SCHEMBL13198414 | 0.89 | KDM1A (0.44) | KDM1AHDAC9 | |
| SCHEMBL19577941 | 0.80 | KDM1A (0.47) | KDM1AMEN1KMT2AAKR1B1SIGMAR1 | |
| SCHEMBL11750121 | 0.79 | KDM1A (0.44) | KDM1AMEN1KMT2AAKR1B1SIGMAR1 | |
| SCHEMBL18088622 | 0.78 | KDM1A (0.46) | KDM1AMEN1KMT2AAKR1B1 | |
| SCHEMBL21376364 | 0.78 | KDM1A (0.46) | KDM1AMEN1KMT2AAKR1B1SIGMAR1 | |
| SCHEMBL10483582 | 0.76 | KDM1A (0.51) | KDM1AMEN1KMT2AAKR1B1SIGMAR1 | |
| SCHEMBL29556050 | 0.76 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1SIGMAR1 | |
| SCHEMBL578812 | 0.76 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1SIGMAR1 | |
| SCHEMBL2590935 | 0.76 | HTR2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102308-A2 | BETA-LACTAMYL VASOPRESSIN V1B ANTAGONISTS | AZEVAN PHARMACEUTICALS, INC. (US) | 2006-09-28 | — | — | WO | disclosed |