SCHEMBL2590935

SCHEMBL2590935

CNC1(C)Cc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13198414 0.79 KDM1A (0.44)
SCHEMBL18088803 0.79 KDM1A (0.44)
SCHEMBL11170654 0.79 MAPT (0.34) HTR2A
Hydrochloric Acid SCHEMBL11188140 0.77 KMT2A (0.35) HTR2A
SCHEMBL8260842 0.76 KDM1A (0.53)
Hydrochloric Acid SCHEMBL11188132 0.76 MAPT (0.33) HTR2A
SCHEMBL13626312 0.75 ALDH1A1 (0.41) HTR2A
SCHEMBL29449822 0.72 HTR2A (0.45) HTR2A
SCHEMBL13804618 0.70 HTR2A (0.34) HTR2A
Ammonia Solution, Strong SCHEMBL3862601 0.70 HTR2A (0.43) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2566850-B1 INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE HYDROBROMIDE SALT RICHTER GEDEON NYRT (HU) 2018-04-11 EP disclosed
EP-2566850-A1 INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS Richter Gedeon Nyrt. (HU) 2013-03-13 EP disclosed
WO-2011138625-A1 INDUSTRIAL PROCESS FOR THE SYNTHESIS OF IVABRADINE SALTS RICHTER GEDEON NYRT. (HU) 2011-11-10 WO disclosed