Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294999 | 0.87 | TACR2 (0.41) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3956308 | 0.84 | TACR2 (0.39) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3956306 | 0.84 | TACR2 (0.39) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5493492 | 0.84 | TACR2 (0.39) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29572531 | 0.84 | TACR2 (0.39) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26602774 | 0.83 | TACR2 (0.38) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL31377482 | 0.83 | TACR2 (0.38) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14446996 | 0.78 | HTR2A (0.39) | HTR2CHTR2A | |
| SCHEMBL13068763 | 0.78 | TACR2 (0.39) | TACR2CA1CA2MEN1KMT2A | |
| SCHEMBL20505538 | 0.77 | TACR2 (0.38) | TACR2CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |