Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5284939 | 0.81 | KMT2A (0.42) | HTR2BCTSSLMNAGID4DRD2 | |
| SCHEMBL23191081 | 0.62 | HTR2B (0.46) | HTR2BPOLBUSP30 | |
| SCHEMBL5278638 | 0.62 | RORC (0.42) | — | |
| SCHEMBL5278640 | 0.62 | RORC (0.42) | — | |
| SCHEMBL17888847 | 0.61 | HTR2B (0.55) | HTR2BPOLB | |
| SCHEMBL17888851 | 0.61 | HRH1 (0.58) | HTR2BPOLB | |
| SCHEMBL6038072 | 0.60 | POLB (0.60) | CTSSLMNAPOLBALDH1A1 | |
| SCHEMBL18781842 | 0.60 | HTR2B (0.56) | HTR2BLMNAPOLB | |
| SCHEMBL20622607 | 0.60 | HTR2B (0.67) | HTR2BPOLBUSP30 | |
| SCHEMBL19957645 | 0.59 | PRMT5 (0.71) | DRD2DRD3CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |