⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL6275422 | 0.96 | — | — | |
| Pyrrolidine SCHEMBL27811068 | 0.85 | — | — | |
| Pyrrolidine SCHEMBL622433 | 0.85 | — | — | |
| Pyrrolidine SCHEMBL2561 | 0.85 | — | — | |
| Pyrrolidine SCHEMBL7827746 | 0.85 | ALDH1A1 (0.89) | — | |
| Pyrrolidine SCHEMBL11288790 | 0.85 | — | — | |
| SCHEMBL576640 | 0.85 | ALDH1A1 (0.89) | — | |
| SCHEMBL3811182 | 0.85 | ALDH1A1 (0.89) | — | |
| Pyrrolidine SCHEMBL148449 | 0.85 | — | — | |
| Pyrrolidine SCHEMBL11536210 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412957-A | Ionic cyclic nitroxyl radical oligomers | 威斯康星州男校友研究基金会 | 2024-01-16 | — | — | CN | disclosed |
| EP-4298090-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | Wisconsin Alumni Research Foundation (US) | 2024-01-03 | — | — | EP | disclosed |
| US-20230006250-A1 | IONIC CYCLIC NITROXYL RADICAL OLIGOMERS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-01-05 | — | — | US | disclosed |
| US-8143287-B2 | Thrombopoietin mimetics | STATEGICS, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100323965-A1 | Thrombopoietin Mimetics | STATEGICS, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| US-7786159-B2 | Thrombopoietin mimetics | STATEGICS, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080139621-A1 | Thrombopoietin Mimetics | STATEGICS, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| EP-0433088-B1 | Monoclonal antibodies reactive with a human atheroma associated antigen | LILLY CO ELI (US) | 1997-06-18 | — | — | EP | disclosed |
| US-5597726-A | Monoclonal antibodies reactive with a human atheroma associated antigen | ELI LILLY AND COMPANY (US) | 1997-01-28 | — | — | US | disclosed |
| US-5264204-A | Hydrophilic free radicals for magnetic resonance imaging | MALLINCKRODT MEDICAL, INC. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993022662-A1 | HYDROPHILIC FREE RADICALS FOR MAGNETIC RESONANCE IMAGING | MALLINCKRODT MEDICAL, INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| US-5196324-A | Use in diagnosis of atherosclerosis | ELI LILLY AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0433088-A1 | Monoclonal antibodies reactive with a human atheroma associated antigen | ELI LILLY AND COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |