Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283011 | 1.00 | POLB (0.32) | POLBSCN9AMEN1GAAKMT2A | |
| SCHEMBL28889722 | 0.80 | SCN9A (0.32) | POLBSCN9A | |
| SCHEMBL3216743 | 0.79 | POLB (0.33) | POLB | |
| SCHEMBL3216751 | 0.79 | POLB (0.33) | POLB | |
| SCHEMBL27823739 | 0.79 | HIF1A (0.32) | — | |
| SCHEMBL28531059 | 0.73 | POLB (0.35) | POLB | |
| SCHEMBL28407299 | 0.73 | KMT2A (0.37) | GAAKMT2A | |
| SCHEMBL15284985 | 0.73 | TSHR (0.42) | GAA | |
| SCHEMBL7808415 | 0.73 | TSHR (0.42) | POLBMEN1GAAKMT2A | |
| SCHEMBL15284981 | 0.73 | TSHR (0.42) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863793-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-07-04 | — | — | EP | disclosed |
| US-7323447-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323447-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-29 | — | — | US | disclosed |
| WO-2006086381-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |