Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 16/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263240 | 0.94 | AGTR1 (0.53) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8263680 | 0.94 | AGTR1 (0.49) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8262237 | 0.94 | AGTR1 (0.52) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8264620 | 0.93 | AGTR1 (0.49) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8263423 | 0.92 | AGTR1 (0.55) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8263666 | 0.90 | AGTR1 (0.50) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8263671 | 0.89 | AGTR1 (0.53) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8263654 | 0.89 | AGTR1 (0.49) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8262298 | 0.87 | AGTR1 (0.59) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL8262502 | 0.87 | AGTR1 (0.59) | AGTR1LTB4R2ABCB11GP6AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079610-A1 | NITROOXY SARTAN DERIVATIVES AS ANGIOTENSIN II RECEPTOR BLOCKERS FOR THE TREATMENT OF CARDIOVASCULAR AND INFLAMMATORY DISEASES | NICOX S.A. (FR) | 2006-08-03 | — | — | WO | disclosed |