⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18764 | 0.60 | — | — | |
| SCHEMBL27995013 | 0.60 | — | — | |
| Ammonia Solution, Strong SCHEMBL28412649 | 0.57 | — | — | |
| SCHEMBL8712085 | 0.57 | — | — | |
| Fluoride SCHEMBL6364058 | 0.57 | — | — | |
| SCHEMBL1998811 | 0.57 | — | — | |
| SCHEMBL1998724 | 0.57 | — | — | |
| SCHEMBL16215461 | 0.57 | — | — | |
| SCHEMBL679693 | 0.57 | — | — | |
| Fluoride Ion SCHEMBL6364056 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657024-B2 | Substituted triazolo-pyrimidine compounds for modulating cell proliferation, differentiation and survival | STATEGICS, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20150307498-A1 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2015-10-29 | — | — | US | disclosed |
| US-9163027-B2 | Substituted triazolo-pyrimidine compounds for modulating cell proliferation differentiation and survival | STATEGICS, INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140142122-A1 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | STATEGICS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8143287-B2 | Thrombopoietin mimetics | STATEGICS, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100323965-A1 | Thrombopoietin Mimetics | STATEGICS, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| US-7786159-B2 | Thrombopoietin mimetics | STATEGICS, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080139621-A1 | Thrombopoietin Mimetics | STATEGICS, INC. (US) | 2008-06-12 | — | — | US | disclosed |